Biological characteristics of tumor grows, types of atypism, similarity and difference of tumors

Plan
Introduction
Infinity of growth
Autonomy of growth
Infiltrating growth
The ability to metastasize
Atypism of tumor cells
Clonal growth
Tumor progression
Conclusion
Literature

Infinity of growth
Redundant proliferation of tumor cells due to the lack of contact inhibition of division («Hayflick barrier»)
Antioncogens Р53
are inactivated
Апоптоз
Tumor cell

Autonomy of growth
The tumor cell is protected from the neuro-humoral effects of the body thanks to autocrine regulation.
Tumor cell
Hormones
Neuron mediators

Infiltrating growth
Germination in the surrounding tissue with their destruction.
In addition, the tumor cell takes from normal cells vitamins, glucose, nitrogen, etc.

Metastasis
The appearance of secondary lesions far from the primary lesion by lymphogenous and hematogenous

Atypia of tumor cells
These are features of the structural and functional organization of tumor cells, creating similarities with embryonic cells and distinguishing them from normal original cells.
Types of atypia:
Morphological;
Biochemical;
Functional;
Immunological.

Clonal growth
Monoclonal growth
Polyclonal growth
gene P53 is supressed
Mutations
Different genotype and phenotype
One general genotype and phenotype

Tumor progression
Irreversible qualitative change in one or more properties of neoplasia, directed upwards with at least some differences between normal and neoplastic tissue
Independent progression of different tumors in one organism
Independent progression of different properties of the same tumor
Progression does not depend on growth
It can be hopping, gradual
It has several alternative ways
The absence of any rules allowing to prognose process and outcome

Conclusion
Based on the foregoing, despite the fact that we have considered only a small part of the features of tumor growth, due to the difficulty of predicting the course and outcome of tumor growth, this topic is relevant and we need to continue to explore this topic further to find ways to treat cancer patients.