Biological characteristics of tumor grows, types of atypism, similarity and difference of tumors

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Plan

Introduction
Infinity of growth
Autonomy of growth
Infiltrating growth
The ability to metastasize
Atypism of tumor cells
Clonal

Plan Introduction Infinity of growth Autonomy of growth Infiltrating growth The ability
growth
Tumor progression
Conclusion
Literature

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Infinity of growth

Redundant proliferation of tumor cells due to the lack of

Infinity of growth Redundant proliferation of tumor cells due to the lack
contact inhibition of division («Hayflick barrier»)

Antioncogens Р53
are inactivated

Апоптоз

Tumor cell

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Autonomy of growth

The tumor cell is protected from the neuro-humoral effects of

Autonomy of growth The tumor cell is protected from the neuro-humoral effects
the body thanks to autocrine regulation.

Tumor cell

Hormones

Neuron mediators

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Infiltrating growth

Germination in the surrounding tissue with their destruction.

In addition, the tumor

Infiltrating growth Germination in the surrounding tissue with their destruction. In addition,
cell takes from normal cells vitamins, glucose, nitrogen, etc.

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Metastasis

The appearance of secondary lesions far from the primary lesion by lymphogenous

Metastasis The appearance of secondary lesions far from the primary lesion by lymphogenous and hematogenous
and hematogenous

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Atypia of tumor cells

These are features of the structural and functional organization

Atypia of tumor cells These are features of the structural and functional
of tumor cells, creating similarities with embryonic cells and distinguishing them from normal original cells.
Types of atypia:
Morphological;
Biochemical;
Functional;
Immunological.

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Clonal growth

Monoclonal growth

Polyclonal growth

gene P53 is supressed
Mutations
Different genotype and phenotype

One general genotype

Clonal growth Monoclonal growth Polyclonal growth gene P53 is supressed Mutations Different
and phenotype

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Tumor progression

Irreversible qualitative change in one or more properties of neoplasia, directed

Tumor progression Irreversible qualitative change in one or more properties of neoplasia,
upwards with at least some differences between normal and neoplastic tissue

Independent progression of different tumors in one organism
Independent progression of different properties of the same tumor
Progression does not depend on growth
It can be hopping, gradual
It has several alternative ways
The absence of any rules allowing to prognose process and outcome

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Conclusion

Based on the foregoing, despite the fact that we have considered only

Conclusion Based on the foregoing, despite the fact that we have considered
a small part of the features of tumor growth, due to the difficulty of predicting the course and outcome of tumor growth, this topic is relevant and we need to continue to explore this topic further to find ways to treat cancer patients.
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