Immune system changes

Generally, immune system is activated in some terms, and deactivated in some terms.
NOTE: this is essential for the mother to not reject the foetus as a foreign body

What all happens?
Monocytes become more active
Number of neutrophils available increases
Number of NK cells increases
Number of T-cells decreases
NOTE: pregnant females are at a higher risk towards infections due to this compromised immune
system during the time of pregnancy

T-cells and NK cells accumulate in uterus
What else?
These act on placenta to aid the passage of nutrients to, and waste from the foetus
NOTE: STAT5 signalling to CD4 T-cells increases to a level far beyond a normal non-pregnant female

Pre-eclampsia
Preeclampsia is defined as the presence of:
systolic blood pressure (SBP) greater than or equal to 140 mm Hg or a diastolic blood pressure (DBP) greater than or equal to 90 mm Hg or higher, on two occasions at least 4 hours apart in a previously normotensive patient,
OR
2. SBP greater than or equal to 160 mm Hg or a DBP greater than or equal to 110 mm Hg or higher (In this case, hypertension can be confirmed within minutes to facilitate timely antihypertensive therapy.