Open science - gerontology

Experiment plan
Total number of mice – 1100
Number of groups - 11
Each group contains 100 mice (for good statistics)
Experiment duration – 2-3 years
Measurement methodology - average, median and maximum life expectancy (chronological age)
Number of researchers in the beginning – 2: Shishparenok A.A., Vekshin N.L.
Data access – full for everyone
Reward - depending on contribution and participation
Project cost: 1) the institute-dependent option (~18055 dollars) and the institute-independent option (~32716 dollars)

Groups
Control
Resveratrol
NMN
Mild intermittent fasting
Metformin
Fisetin
Physical exercises
NMN + Resveratrol
NMN + Resveratrol + Metformin
NMN + Resveratrol + Metformin + Physical exercises + Mild intermittent fasting
Second control (Ad libitum)*
*Mice that will eat a variety of foods and eat them at will at any time. The first control mice cannot eat overnight like other geroprotective groups. Because I need to whet their appetite before breakfast containing eggs, milk and geroprotectors. The second control group of mice will allow me to compare them with the first control group and see how well I have made the diet for the first and other groups. Does it have enough vitamins, minerals and a good ratio of proteins, fats and carbohydrates?
geroprotectors
food restriction
physical exercises