Слайд 2Genetic engineering
1953: J. Watson de-codified the structure of DNA.
It had positive and
negative results.
the access to genetic information of a person can have negative consequences (even discrimination);
main question: should everything that technically possible be allowed?
Слайд 3
GENETIC ENGINEERING
STEPS:
Mapping the Human genome (there are about 20,000 human genes and
“we have only 300 unique genes in the human (genome) that are not in the mouse”)
Determine the role of various elements (“the human genome, a string of 3 billion chemical letters that spell out every inherited trait, is almost identical in all humans: 99.99%) in order to find so called ‘genetics misspellings’ or Single Nucleotide Polymorphisms (SNPs) that lead to genetic diseases or simply differences.
? Pharmacogenomics (creating personalized medicines)
Слайд 4BIOETHICS:
GENETIC ENGINEERING
- How do we conduct experiments?
In every medical experiment the
subject should sign an informed consensus before being treated.
Is it ethical to conduct research in such a field?
Is it ethical to keep secret the findings in such a field when a large number of persons would benefit from the information? Or even for private companies to patent a gene?
Is it ethical to modify genes in order to prevent people from developing diseases? And for parents to decide the sex, or the color of the eyes of their children? Or to add genetically modified capabilities?
Слайд 5BIOETHICS:
GENETIC ENGINEERING
Justifications for Genetic Engineering on Humans:
Utilitarian: we produce an overall
better group of people (Eugenics)
Libertarian: it is a matter of my individual liberty to decide how I want to be
Слайд 6BIOETHICS:
GENETIC ENGINEERING
Problems
A Small Problem of Precedents: Nazism ? what are we
going to do with persons that will not be fit enough for our new genetically-modified standards?
Playing God or Going Against Nature (but imagine this scenario: you (or your wife) are pregnant, and the doctor tells you that your future kid is going to develop dwarfism. But he also says that through genetic-manipulation it would be possible to generate a ‘normal’ baby. What would you do?)