Содержание

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INTRODUCTION

For the safe & efficient use of anaesthetic apparatus, the anaesthetist must

INTRODUCTION For the safe & efficient use of anaesthetic apparatus, the anaesthetist
have a clear concept of the physical aspects of the equipment in use.
Understanding of basic concepts may avert unnecessary accidents & near misses.

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INTRODUCTION

Physics is the world in measurable terms and the physical laws apply

INTRODUCTION Physics is the world in measurable terms and the physical laws
to all states of matter (i.e. solids, liquids and gases).
As anaesthesiolgists we deal with liquids & gases under pressure at varying temperatures and volumes.
These inter-relationships are simple, measurable and their understanding ensures a safe outcome for the patient.

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UNITS OF MEASUREMENT

Base SI units
- length (meter)
- mass (kilogram)
-

UNITS OF MEASUREMENT Base SI units - length (meter) - mass (kilogram)
time (second)
- current (ampere)
- temp (kelvin)
- luminous intensity (candela)
- amount of substance (mole)

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UNITS OF MEASUREMENT

DERIVED UNITS
- temp in degrees celcius
- force (newton)

UNITS OF MEASUREMENT DERIVED UNITS - temp in degrees celcius - force
- pressure (pascal)
- pressure (bar)
- energy (electron volt)
- power (watt)
- frequency (hertz)
- volume ( liter)

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UNITS OF MEASUREMENT

UNITS NOT IN THE SI SYSTEM
- pressure (mmHg)
-

UNITS OF MEASUREMENT UNITS NOT IN THE SI SYSTEM - pressure (mmHg)
pressure (cmh2o)
- pressure (std atmosphere)
- energy (calorie)
- force (kilogram weight)

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UNITS OF MEASUREMENT

- 1 kilopascal = 7.5mmHg.
- 1 Bar =

UNITS OF MEASUREMENT - 1 kilopascal = 7.5mmHg. - 1 Bar =
750mmHg
- 1 kilopascal = 10.2cmH2O
- 1 std atmosphere = 101.325kPa
- 1 calorie = 4.18 J
- 1 kilogram weight = 9.81N
- Pounds / in2(PSI) -Atmospheric Pressure PATM=14.7 PSI)

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PRESSURE

Force = mass x acceleration
= kgms -2 = Newton
Pressure = Force/Area
1

PRESSURE Force = mass x acceleration = kgms -2 = Newton Pressure
Pascal = I Newton acting over 1m2

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PRESSURE

I Bar = 100kPa = Atmospheric pressure at sea level

PRESSURE I Bar = 100kPa = Atmospheric pressure at sea level

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PRESSURE

Normal thumb pressure on a syringe = 25N
2 ml syringe has an

PRESSURE Normal thumb pressure on a syringe = 25N 2 ml syringe
area of 5x10-5
Pressure is 500kPa – extravascular infusion easy

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PRESSURE

With a 20 ml syringe, the pressure exerted is 100kPA = 6X

PRESSURE With a 20 ml syringe, the pressure exerted is 100kPA =
SBP of 120 mmHg (16Kpa)
IVRA – rapid injection – pressure can exceed SBP or cuff pressure – decreased protection

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PRESSURE

Bed Sores --- 20kg of patient mass supported on an area of

PRESSURE Bed Sores --- 20kg of patient mass supported on an area
contact of 100cm2
Force = 196N ( 20kg x 9.81 )
Pressure = 19.6 kPa
Normal SBP = 16kPa --- Risk of Ischemia

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PRESSURE

Pressure relief valves and expiratory valves
Pressure in the circuit exerts a force

PRESSURE Pressure relief valves and expiratory valves Pressure in the circuit exerts
on the diaphragm. If this force is greater that the force exerted by the valve, air escapes through the exp valve. They are typically low pressure valves(50Pa)

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GAUGE AND ABSOLUTE PRESSURE

Full oxygen cylinder has a gauge pressure of 137

GAUGE AND ABSOLUTE PRESSURE Full oxygen cylinder has a gauge pressure of
bar
Empty cylinder still has oxygen at atmospheric pressure
Absolute Pressure = 138 bar

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GAUGE PRESSURE

Absolute P = Gauge P + Atmospheric P
Most times we ignore

GAUGE PRESSURE Absolute P = Gauge P + Atmospheric P Most times
atmospheric P
Thus, ventilator pressures, gas cylinder pressures and arterial blood pressures are all gauge pressures

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PRESSURE

For ideal gases (air, nitrogen, oxygen)-Full cylinder pressure = 2000 PSI -Full

PRESSURE For ideal gases (air, nitrogen, oxygen)-Full cylinder pressure = 2000 PSI
cylinder volume= 660 liters
1000 PSI --> 330 L500 PSI-->165 L
Volume remaining is proportional to pressure

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FLUID FLOW

Flow = quantity of fluid/gas passing a point in unit time
Can

FLUID FLOW Flow = quantity of fluid/gas passing a point in unit
be turbulent or laminar

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LAMINAR FLOW

Flow moves in a steady manner with no eddies or turbulence
Flow

LAMINAR FLOW Flow moves in a steady manner with no eddies or
is greatest in the centre
Zero flow at the wall
P/F = constant known as the resistance of the apparatus or tube
Hagen- Poiseuille Equation

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LAMINAR FLOW

Flow = ∏Pd4/128ųl
P = Pressure
d = Diameter
Ų = viscosity
L = length

LAMINAR FLOW Flow = ∏Pd4/128ųl P = Pressure d = Diameter Ų

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THE ANESTHESIA MACHINE

The resistance to flow is a function of the viscosity

THE ANESTHESIA MACHINE The resistance to flow is a function of the
of the gas, the length of the pipe and the radius of the pipe to the fourth power
Called Poiseuille’s Law
A 7.0 ETT has almost twice the resistance of an 8.0 ETT

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THE ANESTHESIA MACHINE

THE ANESTHESIA MACHINE

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TURBULENT FLOW

Swirls or eddies present
Resistance is higher than laminar flow
Reynold’s Number =

TURBULENT FLOW Swirls or eddies present Resistance is higher than laminar flow
vpd/µ (velocity x pressure x density)/viscosity
Re Number > 2000 = Turbulent Flow
ET connector/ Kinked ETT
Use of Helium reduces the density

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TURBULENT FLOW

Most important property is density which is mass/volume

TURBULENT FLOW Most important property is density which is mass/volume

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CRITICAL FLOW

Critical flow for a typical anesthetic gas has approx the same

CRITICAL FLOW Critical flow for a typical anesthetic gas has approx the
numerical value as the diameter of the airway concerned
9mm ETT has a critical flow of 9L/min
Above 9L/min = turbulent flow

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CRITICAL FLOW

Air has a lower density than Nitrous Oxide – laminar flow

CRITICAL FLOW Air has a lower density than Nitrous Oxide – laminar
prevails
Air flow through the smaller airways is slower – laminar flow predominates
Corrugated surfaces induces turbulence at low flow rates

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CRITICAL FLOW

Although the bronchi and smaller air passages are narrower than the

CRITICAL FLOW Although the bronchi and smaller air passages are narrower than
trachea, the air flow through them is slower.
Laminar flow is usual in the LRT

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TENSION

Tension is a tangential force in Nm acting on a length of

TENSION Tension is a tangential force in Nm acting on a length
wall
A balance must be present between the pressure caused by the smooth muscle and elastic tissue and the fluid pressure in the tube to prevent the tube progressively distending or collapsing

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TENSION

A fall in pressure in an arteriole tends to distend it less

TENSION A fall in pressure in an arteriole tends to distend it
and so would reduce its radius but the smooth muscle in the wall maintains tension.
Ratio of tension to radius is increased and pressure across the wall is raised (La Place’s law)

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SURFACE TENSION

Pressure = 2T/R ( wall of a sphere)
Surfactant decreases surface tension

SURFACE TENSION Pressure = 2T/R ( wall of a sphere) Surfactant decreases
lining the alveoli – makes surface tension variable
Tension decreases as the alveoli contract and increase as the alveoli distend

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SURFACE TENSION

On the surface of a liquid, some of the forces of

SURFACE TENSION On the surface of a liquid, some of the forces
attraction between molecules act in a direction parallel to the surface
Also forces between molecules and the walls – results in a meniscus
Water – concave meniscus
Mercury – convex meniscus

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THE ANESTHESIA MACHINE

Tension in the wall of the bag equals Pressure x

THE ANESTHESIA MACHINE Tension in the wall of the bag equals Pressure
Radius x ½ ( T = PxR /2 )
For a cylindrical structure such as an artery, the wall tension = PxR

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BERNOULLI PRINCIPLE

Fall in pressure at a narrowing of a tube
Gas/Fluid has potential

BERNOULLI PRINCIPLE Fall in pressure at a narrowing of a tube Gas/Fluid
energy in the form of its pressure and kinetic energy associated with its flow
At the narrowing – increase in fluid velocity – increase in kinetic energy

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BERNOULLI PRINCIPLE

Therefore decrease in potential energy
If this pressure falls below atmospheric pressure,

BERNOULLI PRINCIPLE Therefore decrease in potential energy If this pressure falls below
can entrain gas/fluid via the side hole at the constriction
Example is a nebulizer and the oxygen mask

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THE GAS LAWS

Boyles Law
Charles Law
Third Perfect Gas Law
Dalton’s Law of Partial Pressures
Universal

THE GAS LAWS Boyles Law Charles Law Third Perfect Gas Law Dalton’s
Gas Constant

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BOYLES LAW

At constant temp, V ∞ 1/P
How much oxygen is available at

BOYLES LAW At constant temp, V ∞ 1/P How much oxygen is
atmospheric pressure in a tank?
Internal capacity of cylinder = 10L
Absolute Pressure = 138 bar
Therefore, volume = 1380L
P1V1 = P2V2
13800kPa x 10L = 100kPa x 1380L

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CHARLES LAW

At constant pressure, V∞Temp
Gases expand when heated

CHARLES LAW At constant pressure, V∞Temp Gases expand when heated

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THIRD PERFECT GAS LAW

At constant volume, P ∞ Temp
STP – 273.15K and

THIRD PERFECT GAS LAW At constant volume, P ∞ Temp STP – 273.15K and 101.325kPa
101.325kPa

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ADIABATIC CHANGE

The three gas laws describe the behaviour of a gas when

ADIABATIC CHANGE The three gas laws describe the behaviour of a gas
one of the three variables (pressure, temp or volume) is constant.
For these conditions to apply, heat energy is required to be added or be taken from a gas
The state of a gas can also be altered without allowing the gas to exchange heat energy with its surroundings

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ADIABATIC CHANGE

The state of a gas can be altered without allowing the

ADIABATIC CHANGE The state of a gas can be altered without allowing
gas to exchange heat energy with its surroundings
An example is the use of the cryoprobe
If a gas cylinder connected to an anesthetic machine is turned on quickly, the pressure of gas in the connecting pipes and gauges rises rapidly

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ADIABATIC CHANGE

Thus, the gas is compressed adiabatically and a large temp rise

ADIABATIC CHANGE Thus, the gas is compressed adiabatically and a large temp
with the associated risk of fire can occur

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DALTON’S LAW OF PARTIAL PRESSURES

In a mixture of gases, the pressure exerted

DALTON’S LAW OF PARTIAL PRESSURES In a mixture of gases, the pressure
by each gas is the same as that which it would exert if it alone occupied the container

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AVOGADRO’S NUMBER

States that equal volumes of gases at the same temp and

AVOGADRO’S NUMBER States that equal volumes of gases at the same temp
pressure contain equal number of molecules
Avogadro’s number = 6.022 x 1023
One mole of any gas occupies 22.4L at STP

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BREATHING SYSTEMS

Breathing Circuitsa)Open (non-rebreathing) •Simple face mask or nasal cannula (CO2 diffuses

BREATHING SYSTEMS Breathing Circuitsa)Open (non-rebreathing) •Simple face mask or nasal cannula (CO2
away from the face) •Bag-Valve-Mask system (Ambu®): uses 3 valves to allow either spontaneous or controlledventilation while preventing rebreathing b)Semi-Open (Mapleson / Bain)•Most efficient removal of CO2 for a given gas flow when the "pop off" valve is nearest the source of the ventilatory power -Spontaneous ventilation: Mapleson A -Controlled ventilation: Mapleson D•However, the "A" system is very inefficient (requires high gas flows) to prevent rebreathing during controlled ventilation, while the "D" system is reasonably efficient for both controlled and spontaneous ventilation, so the "D" is preferred for most applications. -Bain circuit is a coaxial Mapleson Dc)Semi Closed Circle System •Patient gas uptake < fresh gas flow < minute ventilation •Some rebreathing of exhaled gas (following removal of CO2 by absorber)d)Closed System •Gas inflow = Patient Uptake •If using sidestream agent / CO2 analyzer, must route exhaust back into circuit •Starting values-O2: 3-4 ml/kg/min

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AVOGADRO’S NUMBER

Typical Nitrous cylinder has 3.4kg of Nitrous Oxide
Molec wt = 44

AVOGADRO’S NUMBER Typical Nitrous cylinder has 3.4kg of Nitrous Oxide Molec wt
( 1 mole)
1 mole occupies 22.4L at STP
3400g occupies 22.4 x 3400/44 = 1730L

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UNIVERSAL GAS CONSTANT

PV = nRT
In a cylinder, the volume and temp is

UNIVERSAL GAS CONSTANT PV = nRT In a cylinder, the volume and
constant
Therefore, P is ∞ n
Implies that the pressure gauge acts as a contents gauge if the cylinder contains a gas

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CRITICAL TEMP

Defined as the temp above which a substance cannot be liquefied

CRITICAL TEMP Defined as the temp above which a substance cannot be
however much pressure is applied
Critical Pressure is the vapour pressure at the critical temp
Critical temp for nitrous is 36.5 degrees – it is a gas if the temp is above 36.5

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CRITICAL TEMP

Critical temp for oxygen is -119 degrees
Impossible to turn oxygen into

CRITICAL TEMP Critical temp for oxygen is -119 degrees Impossible to turn
its liquid form at room temp

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SOLUBILITY

When a liquid is placed in a closed container, an equilibrium is

SOLUBILITY When a liquid is placed in a closed container, an equilibrium
eventually established at the surface between the vapour of the liquid and the liquid itself.
In this equilibrium state, the partial pressure exerted by the vapour is known as saturated vapour pressure

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SOLUBILITY

Saturated Vapour Pressure
Henry’s Law – states that at a particular temp, the

SOLUBILITY Saturated Vapour Pressure Henry’s Law – states that at a particular
amt of a given gas dissolved in a given liquid is directly proportional to the partial pressure of the gas in equilibrium with the liquid
As a liquid is warmed, less gas dissolves in it --- may see bubbles ( Blood warmer)

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SOLUBILITY

The effect of high pressure on the solubility of nitrogen is particularly

SOLUBILITY The effect of high pressure on the solubility of nitrogen is
relevant to deep sea divers as nitrogen if breathed under pressure passes into solution in the tissues
If a return to atmospheric pressure is made too rapidly, the nitrogen comes out of solution as small bubbles in the joints and elsewhere

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SOLUBILITY

Ostwald Solubility Coefficient is the volume of gas which dissolves in one

SOLUBILITY Ostwald Solubility Coefficient is the volume of gas which dissolves in
unit volume of the liquid at the temp concerned
Independent of pressure

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SOLUBILITY

Partition Coefficient is defined as the ratio of the amount of substance

SOLUBILITY Partition Coefficient is defined as the ratio of the amount of
present in one phase compared with another, the 2 phases being of equal volume and in equilibrium

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SOLUBILITY

Ether has the highest Ostwald Solubility Coefficient (12). Halothane is 2.3 and

SOLUBILITY Ether has the highest Ostwald Solubility Coefficient (12). Halothane is 2.3
Nitrous is 0.47
Ether carried away more rapidly from the lungs – conc of ether builds up more slowly in the alveoli --- slower induction of anesthesia

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SOLUBILITY

Second Gas effect
Diffusion hypoxia

SOLUBILITY Second Gas effect Diffusion hypoxia

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SECOND GAS EFFECT

During the inspiration of a gas mixture containing nitrous oxide,

SECOND GAS EFFECT During the inspiration of a gas mixture containing nitrous
the N2O is absorbed into the bloodstream faster than the oxygen or nitrogen.
So at peak inspiration, when the pressure in the alveoli has equalized with the ambient pressure, there is a net surplus of oxygen and N2 molecules

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DIFFUSION HYPOXIA

At the end of an anesthetic using N2O, the N2O diffuses

DIFFUSION HYPOXIA At the end of an anesthetic using N2O, the N2O
faster into the alveoli diluting the gases there ---- leads to a fall in oxygen concentration

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SOLUBILITY

Fat is an impt constituent of tissue
Oil is therefore used for measurements
Agents

SOLUBILITY Fat is an impt constituent of tissue Oil is therefore used
with the highest oil solubility have the greatest potency
Halothane = 224
Nitrous Oxide = 1.4
Sevoflurane = 55
Desflurane = 18.7

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SOLUBILITY

High solubility = lower MAC values
Anesthetics tend to interfere with the molecular

SOLUBILITY High solubility = lower MAC values Anesthetics tend to interfere with
configuration of the long fatty acid at a critical point within the neurones
Attachment to the chain is loose and readily reversible with Van der Waals forces

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SOLUBILITY

Also attach to the long carbon chain molecules present in rubber and

SOLUBILITY Also attach to the long carbon chain molecules present in rubber and plastics
plastics

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DIFFUSION AND OSMOSIS

Diffusion is the process by which the molecules of a

DIFFUSION AND OSMOSIS Diffusion is the process by which the molecules of
substance transfer through a layer such as the surface of a solution
What is more likely to happen if diffusing capacity in the lungs are decreased?

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DIFFUSION

Pulmonary Diffusing Capacity
Rate at which CO leaves the alveoli is dependent on

DIFFUSION Pulmonary Diffusing Capacity Rate at which CO leaves the alveoli is
the rate of diffusion through the membrane and not on pulmonary blood flow
Sarcoidosis, Asbestosis

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EFFECT OF MOLECULAR SIZE

Grahams Law states that the rate of diffusion of

EFFECT OF MOLECULAR SIZE Grahams Law states that the rate of diffusion
a gas is inversely proportional to the square root of its molecular weight
Example – Injection of local anesthetics – inject as close as possible to the nerve because diffusion only allows limited penetration of the LA into the tissues

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OSMOLARITY

Is the sum total of the molarities of the solutes in a

OSMOLARITY Is the sum total of the molarities of the solutes in
solution
RL has an osmolarity of 278mosm/l (Na 131, K 5, Cl 111, Ca 2, Lactate 29
Plasma has an osmolarity of 300 >99% due to Na, Cl, HCO3. Plasma proteins account for 1 mosm/l

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OSMOLARITY

If a patient is transfused hypotonic fluids – get changes in the

OSMOLARITY If a patient is transfused hypotonic fluids – get changes in
osmotic pressure gradient across cell membranes – fluid diffuses into cells.
Albumin and globulin give rise to an oncotic pressure of 26mmHg
Decreased oncotic pressure – decreased gradient at the venous end - edema

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OSMOLARITY

Number of osmoles per kg of water or clear solution
Avoids the effect

OSMOLARITY Number of osmoles per kg of water or clear solution Avoids
of temp which affects volume

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HEAT CAPACITY

Specific Heat Capacity is defined as the amount of heat required

HEAT CAPACITY Specific Heat Capacity is defined as the amount of heat
to raise the temp of 1kg of a substance by 1 kelvin. J per kg per kelvin
Heat Capacity is the amount of heat required to raise the temp of a given object by 1 kelvin.

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HEAT CAPACITY

Body temp = 36 degrees
Shivers – increases heat production 4 fold

HEAT CAPACITY Body temp = 36 degrees Shivers – increases heat production
to 320W. Basal level of heat production is 80 W
An extra 240W = 14.4 kJ/min
245kJ needed to increase temp by 1 degree . (total heat capacity = 3.5 x 70kg)

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HEAT CAPACITY

This patient will need to shiver for 17 minutes to produce

HEAT CAPACITY This patient will need to shiver for 17 minutes to
the heat required to do this

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HEAT CAPACITY

Specific Heat Capacity of blood = 3.6kJ/kg/C
Transfuse 2L of blood at

HEAT CAPACITY Specific Heat Capacity of blood = 3.6kJ/kg/C Transfuse 2L of
5 degrees
Warmed to 35 degrees in the patient

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HEAT CAPACITY

Heat Required = 216kJ (2x3.6x30)
Heat Capacity of 70kg person = 245kJ/C
Therefore

HEAT CAPACITY Heat Required = 216kJ (2x3.6x30) Heat Capacity of 70kg person
temp must fall by 1 degree

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THE ANESTHESIA MACHINE

THE ANESTHESIA MACHINE

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THE ANESTHESIA MACHINE

N2O is stored in the tank as a liquid in

THE ANESTHESIA MACHINE N2O is stored in the tank as a liquid
equilibration with the N2O gas above it.
As we draw N2O gas from the tank, it is replaced with gas that boils off from the liquid below it.
The heat required for this phase transition is drawn from the cylinder which draws it from the air around the tank
Results in the cylinder cooling

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THE ANESTHESIA MACHINE

Why does the pressure go down as the gas cools?

THE ANESTHESIA MACHINE Why does the pressure go down as the gas cools?

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THE ANESTHESIA MACHINE

The pressure in the tank reflects the force of the

THE ANESTHESIA MACHINE The pressure in the tank reflects the force of
molecules bouncing off every part of the wall tank.
Pressure = Force of the molecules as they bounce off the surface divided by the surface area of the tank.
Force of each molecule reflects the thermal energy of the molecule.

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THE ANESTHESIA MACHINE

Thermal energy is taken out of the nitrous tank by

THE ANESTHESIA MACHINE Thermal energy is taken out of the nitrous tank
heat of vaporization.
Therefore, the collision between each molecule and the wall of the tank is less energetic ---- therefore the pressure drops
Gay- Lussac’s Law – pressure is inversely related to temperature when volume is constant

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THE ANESTHESIA MACHINE

As oxygen is drawn from the tank, both the temp

THE ANESTHESIA MACHINE As oxygen is drawn from the tank, both the
and pressure drop over time.
The pressure drops because we are removing gas from the tank
The temp drops because the released molecules take their thermal energy with them – also contributes to the loss of pressure

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CIRCULATION

Ohm’s Law
Pressure = Flow x Resistance
Voltage = Current x Resistance
Resistance = Pressure/Flow

CIRCULATION Ohm’s Law Pressure = Flow x Resistance Voltage = Current x Resistance Resistance = Pressure/Flow

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CIRCULATION

SVR = (MAP – CVP)/CO
Poiseulle’s equation – Resistance to flow is proportional

CIRCULATION SVR = (MAP – CVP)/CO Poiseulle’s equation – Resistance to flow
to 1/r4
Arterial blood pressure is measured
- by the auscultatory method
- by the oscillometric method
- invasively

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CIRCULATION

P = 2T/R
Failing heart – Increase in R and therefore a decrease

CIRCULATION P = 2T/R Failing heart – Increase in R and therefore
in P. Unable to increase T
Normal Heart – Increase in R due to increased VR. Also get an increase in T (Frank Starling). Therefore no change in P

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CIRCULATION

MAP dependent on SVR and CO
Patient with a decreased SVR, a high

CIRCULATION MAP dependent on SVR and CO Patient with a decreased SVR,
BP indicates an increased CO
In a patient with an increased SVR, a high BP indicates a decreased CO

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AUSCULTATORY METHOD

Based on the Korotkoff sounds
The systolic and diastolic pressures are determined

AUSCULTATORY METHOD Based on the Korotkoff sounds The systolic and diastolic pressures
and the mean is calculated
MAP = DBP +1/3PP
Not readily calibrated

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OSCILLOMETRIC METHOD

Based on pressure waveform in an air filled cuff coupled to

OSCILLOMETRIC METHOD Based on pressure waveform in an air filled cuff coupled
the arterial pulse
Primarily determines MAP which is the point of maximum oscillation
Systolic and diastolic is inferred from the MAP

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INVASIVE MONITORING

Transducer is a strain gauge that linearly converts pressure to electrical

INVASIVE MONITORING Transducer is a strain gauge that linearly converts pressure to
resistance
The monitor measures the electrical resistance and calculates the corresponding pressure
Compensate for atmospheric pressure by exposing the back side of the strain gauge to air

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INVASIVE MONITORING

Strain Gauge – movements of the diaphragm alter the tension in

INVASIVE MONITORING Strain Gauge – movements of the diaphragm alter the tension
the resistance wire – changes resistance – changes current flow – amplified and displayed on an oscilloscope

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INVASIVE MONITORING

Wheatstone Bridge
4 resistors, a source and a galvanometer
Variable resistor can be

INVASIVE MONITORING Wheatstone Bridge 4 resistors, a source and a galvanometer Variable
zeroed – adjusted until there is a null deflection on the galvanometer
Strain gauge resistor

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INVASIVE MONITORING

What does it mean to “zero” the transducer?

INVASIVE MONITORING What does it mean to “zero” the transducer?

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INVASIVE MONITORING

The act of zeroing the transducer tells the monitor the electrical

INVASIVE MONITORING The act of zeroing the transducer tells the monitor the
resistance that should be considered zero pressure
What you are correcting for is
- minor imperfections in the calibration of the strain gauge
- the column of water between the left atrium and the transducer

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INVASIVE MONITORING

Column of water between the point that is opened to air

INVASIVE MONITORING Column of water between the point that is opened to
and the transducer itself
Force that this water exerts on the strain gauge is subtracted from the subsequent force measured by the transducer
Establishes a net pressure in the blood vessel relative to this point

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CARDIAC OUTPUT

Gold standard for measuring cardiac output is by applying Fick’s Law

CARDIAC OUTPUT Gold standard for measuring cardiac output is by applying Fick’s
to oxygen flow
Net flow of oxygen into blood as it courses through the lungs = 200mls/min
Net flow of oxygen out of the lungs = cardiac output x (Arterial oxygen content – Mixed venous oxygen content)

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PULSE OXIMETRY

Beer Lambert Law
Absorption of light = Concentration x Thickness x extinction

PULSE OXIMETRY Beer Lambert Law Absorption of light = Concentration x Thickness
coefficient
Has two diodes
At 660nm, little absorption by oxyhemoglobin
At 940nm, little absorption by deoxyhemoglobin

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PULSE OXIMETRY

Beer’s Law states that the absorption of radiation by a given

PULSE OXIMETRY Beer’s Law states that the absorption of radiation by a
thickness of a solution of a given concentration is the same as that of twice the thickness of a solution of half the concentration

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PULSE OXIMETRY

Lambert’s Law states that each layer of equal thickness absorbs an

PULSE OXIMETRY Lambert’s Law states that each layer of equal thickness absorbs
equal fraction of radiation which passes through it

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PULSE OXIMETRY

The diodes alternate at about 100 times a second between 660nm,

PULSE OXIMETRY The diodes alternate at about 100 times a second between
940nm and off
A single photocell on the opposite side of te tissue records the transmitted signal and sends it to the microprocessor

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PULSE OXIMETRY

Two parts to the waveform
- static component which represents the

PULSE OXIMETRY Two parts to the waveform - static component which represents
absorption of the tissue, venous blood, nail polish, etc
- oscillating component which represents the absorption by arterial blood

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PULSE OXIMETRY

On the assumption that the tissue thickness is the same for

PULSE OXIMETRY On the assumption that the tissue thickness is the same
both oxyHb and deoxyHb, the microprocessor solves two simultaneous equations for the relative concentrations of oxyHb and deoxyHb

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PULSE OXIMETRY

PULSE OXIMETRY

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PULSE OXIMETRY

Unable to distinguish more that two types of Hb
Cannot identify carboxyHb

PULSE OXIMETRY Unable to distinguish more that two types of Hb Cannot
--- to the pulse oximeter, it appears to be 90% oxyHb, 10% deoxyHb
MetHb is interpreted as 85% oxyHb and 15% deoxyHb
A proper blood gas machine has 9 to 13 wavelengths to distinguish multiple Hb moieties

Слайд 98

ELECTRICAL SAFETY

Two major hazards
- burns
- arrhythmias

ELECTRICAL SAFETY Two major hazards - burns - arrhythmias

Слайд 99

ELECTRICAL SAFETY

Three types of electrical current
- macroshock
- microshock
-

ELECTRICAL SAFETY Three types of electrical current - macroshock - microshock - radiofrequency currents
radiofrequency currents

Слайд 100

ELECTRICAL SAFETY

A power station supplies electricity at very high voltage to a

ELECTRICAL SAFETY A power station supplies electricity at very high voltage to
substation where the voltage is reduced by a transformer.
Current the passes to the hospital along 2 wires – live and neutral. The neutral wire is connected to earth at the substation
Mains electric sockets in the hospital provide connections to the live and neutral conductors and also to a third conductor

Слайд 101

ELECTRICAL SAFETY

Third conductor is connected to earth at the hospital.
If a person

ELECTRICAL SAFETY Third conductor is connected to earth at the hospital. If
touches a live wire at the hospital, an electric current can be completed through the body, through the earth and back to the substation

Слайд 102

ELECTRICAL SAFETY

1 mA = tingling sensation on touching the live parts of

ELECTRICAL SAFETY 1 mA = tingling sensation on touching the live parts
the apparatus
Current which flow through the anesthetist depends on the impedence presented to this flow
Impedence of antistatic footwear and the floor is about 240kohms
Current is therefore less than 1mA

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ELECTRICAL SAFETY

If you are wearing non standard footwear and standing in a

ELECTRICAL SAFETY If you are wearing non standard footwear and standing in
pool of saline on the floor while in contact with faulty equipment, a higher current flows.
A current of greater than 1mA flows. A current of 24 mA would result in being unable to release your hand from the equipment.

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ELECTRICAL SAFETY

Most of the impedence now occurs at the points of contact

ELECTRICAL SAFETY Most of the impedence now occurs at the points of
with the skin and the feet with the shoes. May be around 5kohms
Current = 120 volts/ 5000ohms x1000
= 24mA

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ELECTRICAL SAFETY

Risk of VF
Risk is much greater if the current passes through

ELECTRICAL SAFETY Risk of VF Risk is much greater if the current
the heart during repolarization – early T wave of the EKG
Mains alternating current of 50 Hz is more dangerous than high frequency current of 1kHz or greater
Underlying myocardial disease

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CLASS 1 EQUIPMENT

Any conducting part that is accessible to the user, such

CLASS 1 EQUIPMENT Any conducting part that is accessible to the user,
as the metal case of an instrument, is connected to an earth wire which becomes the third wire connected via the plug to the mains supply socket
If a fault occurs, a high current flows which melts a protecting fuse and disconnects the circuit

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CLASS 2

Double insulated equipment
All accessible parts are protected by 2 layers of

CLASS 2 Double insulated equipment All accessible parts are protected by 2
insulation or reinforced insulation
An earth wire is not required

Слайд 108

CLASS 3

Internally powered equipment
Has its own power source located within the equipment
Although

CLASS 3 Internally powered equipment Has its own power source located within
the risk of electric shock may still be present, the particular risks associated with mains electricity are avoided

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ISOLATED PATIENT CIRCUITS

Some equipment requires electrical connections be made to the patient

ISOLATED PATIENT CIRCUITS Some equipment requires electrical connections be made to the
(monitors)
A deliberate attempt is made to reduce the impedance at the junction between the electrode and the skin
Decreases the protection that the skin might otherwise offer

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ISOLATED PATIENT CIRCUITS

To counteract this, use an isolated patient circuit or a

ISOLATED PATIENT CIRCUITS To counteract this, use an isolated patient circuit or
floating circuit
The electrical circuit is divided into two parts – a mains part which contains a power supply driven directly by the mains and an isolated part which is separated from the mains part by an electrical barrier

Слайд 111

ISOLATED PATIENT CIRCUIT

Intended to provide protection should a fault develop in the

ISOLATED PATIENT CIRCUIT Intended to provide protection should a fault develop in
mains part and to reduce flow of mains leakage currents in the patient circuit.

Слайд 112

LEAKAGE CURRENT STANDARDS

Electromedical equipment is classified according to the maximum leakage current

LEAKAGE CURRENT STANDARDS Electromedical equipment is classified according to the maximum leakage
permissible for particular applications
CF – electrodes which may contact the heart directly. Indicates cardiac use and a floating circuit. Leakage current should be less than 50uA

Слайд 113

LEAKAGE CURRENT STANDARDS

B or BF it it has a floating circuit. Leakage

LEAKAGE CURRENT STANDARDS B or BF it it has a floating circuit.
current of 500uA
All new equipment in a hospital is subjected to an acceptance test which will verify leakage currents.

Слайд 114

ELECTRICAL SAFETY

Electrical currents flow in circuits
A path must exist from the electrical

ELECTRICAL SAFETY Electrical currents flow in circuits A path must exist from
source to the patient and another path from the patient back to the electrical source for a shock hazard to exist
Ohm’s Law I = V/R
Current density is the amount of current flowing per unit area

Слайд 115

ELECTRICAL SAFETY

Standardized voltage is about 120V
The “120” is the root mean square

ELECTRICAL SAFETY Standardized voltage is about 120V The “120” is the root
voltage
Alternating current cycles at 60 Hz
Average voltage is therefore 0
If one squares all the voltages and the takes the average, the result is 120V
The peak voltage is about 150V – is the potential driving energy

Слайд 116

ROOT MEAN SQUARE

If all the values of the sine wave are squared,

ROOT MEAN SQUARE If all the values of the sine wave are
all the amplitudes are converted to positive numbers
By taking the mean of this, a value is obtained which is related to the amplitude of the wave
Square root of this figure is the equivalent DC value

Слайд 117

MACROSHOCK

Potential for both burns and arrhythmias
Current must flow through the thorax
In the

MACROSHOCK Potential for both burns and arrhythmias Current must flow through the
thorax it is split between the chest wall and the great vessels – delivers the current density to the myocardium.

Слайд 118

MACROSHOCK- FACTORS FOR ELECTROCUTION

Patient unclothed and wet
Patient is on a large metal

MACROSHOCK- FACTORS FOR ELECTROCUTION Patient unclothed and wet Patient is on a
table, frequently electrically operated
Patient is surrounded by electrical devices. These electrical devices are exposed to spilled fluids and operator abuses
Anesthetized patient is unable to respond or withdraw from an electric shock

Слайд 119

MACROSHOCK

How much current can we deliver to the anesthetized patient?

MACROSHOCK How much current can we deliver to the anesthetized patient?

Слайд 120

MACROSHOCK

Patient may receive 150 volts with direct contact
The current he receives will

MACROSHOCK Patient may receive 150 volts with direct contact The current he
depend on the resistance to flow ( I = V/R )
Main resistance to flow is the skin
Resistance of dry skin is 50000 ohms
Current through dry skin is 150V/50 000 which is 0.003A or 3 mA

Слайд 121

MACROSHOCK

Current required to produce VF is 80mA
Therefore 3mA will not cause VF
Resistance

MACROSHOCK Current required to produce VF is 80mA Therefore 3mA will not
of wet skin is about 500 – 1000 ohms ( this is also about the resistance of EKG electrodes)
Current could therefore be 300mA ----- VF is a major risk

Слайд 122

MACROSHOCK

What is the voltage required to produce an 80mA current across wet

MACROSHOCK What is the voltage required to produce an 80mA current across
skin?
V = I x R ----- 500 x 80 = 40 volts

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MACROSHOCK

How could a patient come into contact with 40 volts in the

MACROSHOCK How could a patient come into contact with 40 volts in the OR?
OR?

Слайд 124

MACROSHOCK

MACROSHOCK

Слайд 125

MACROSHOCK

Hot and neutral leads power the device
Ground lead connects to the chassis

MACROSHOCK Hot and neutral leads power the device Ground lead connects to
of the device to return any leaking current back to the ground
If the chassis is properly grounded, then current will flow through the ground wire which has very little resistance – current will be high and a fuse will blow

Слайд 126

MACROSHOCK

MACROSHOCK

Слайд 127

MACROSHOCK

To avoid helping electrocute the patient, no properly functioning modern monitoring device

MACROSHOCK To avoid helping electrocute the patient, no properly functioning modern monitoring
will complete a circuit between the patient and ground
The ground plate on the electrocautery unit is merely the return electrode and not a true ground
NOT GROUNDING PATIENTS IS AN IMPORTANT ASPECT OF ELECTRICAL SAFETY IN THE OR

Слайд 128

MACROSHOCK

Equipment must be designed so the the hot wire cannot easily short

MACROSHOCK Equipment must be designed so the the hot wire cannot easily
out with the chassis
Every chassis must be grounded
Ground wires must be regularly inspected
Patient should not be connected to potential grounds
Line Isolation Monitors

Слайд 129

LINE ISOLATION TRANSFORMER

Simple device that prevents a circuit from being completed by

LINE ISOLATION TRANSFORMER Simple device that prevents a circuit from being completed by connection to ground
connection to ground

Слайд 130

LINE ISOLATION TRANSFORMER

LINE ISOLATION TRANSFORMER

Слайд 131

LINE ISOLATION TRANSFORMER

How do you monitor a line isolation transformer to see

LINE ISOLATION TRANSFORMER How do you monitor a line isolation transformer to
if there is any connection between both wire and ground?

Слайд 132

LINE ISOLATION TRANSFORMER

LINE ISOLATION TRANSFORMER

Слайд 133

LINE ISOLATION MONITOR

Resistor has a resistance of about 150 000 ohm’s so

LINE ISOLATION MONITOR Resistor has a resistance of about 150 000 ohm’s
that the maximum current that can pass through the circuit is 1mA
When the resistance detected by the Lim falls to less than 75 000 ohm’s, a warning is signalled ---- should the other line come into full contact with ground, a current of 2mA could flow

Слайд 134

MICROSHOCK

Refers to currents delivered directly to the myocardium via intracardiac electrodes or

MICROSHOCK Refers to currents delivered directly to the myocardium via intracardiac electrodes
catheters.
Minimum fibrillation threshold is 10 microamps

Слайд 135

MICROSHOCK

How much safety does the isolation transformer provide against microshock hazard?

MICROSHOCK How much safety does the isolation transformer provide against microshock hazard?

Слайд 136

MICROSHOCK

Ground wire should be intact
LIM signals a warning if the resistance between

MICROSHOCK Ground wire should be intact LIM signals a warning if the
the ground and either wire is less than 75 000 ohm’s, which corresponds to a 2mA current running through the ground wire

Слайд 137

MICROSHOCK

In the presence of a LIM, it takes two shorts to the

MICROSHOCK In the presence of a LIM, it takes two shorts to
chassis of two devices, with both ground wires broken, to detect a macroshock hazard
A single short to the chassis of the device with a broken ground can create an undetected microshock hazard

Слайд 138

ELECTROCAUTERY

Current density = current flow per unit area
Explains the heating effect of

ELECTROCAUTERY Current density = current flow per unit area Explains the heating
the electrosurgical equipment
Passage of direct current or low frequent alternating current may cause physical sensation, stimulate muscular contraction and gives a risk of VF

Слайд 139

ELECTROCAUTERY

These effects become less as the frequency of the current increases being

ELECTROCAUTERY These effects become less as the frequency of the current increases
small above 1 kHz and negligible above 1 MHz. The burning and heating effect can occur at all frequencies

Слайд 140

ELECTROCAUTERY

Electrosurgical equipment is used to pass a current of a high frequency

ELECTROCAUTERY Electrosurgical equipment is used to pass a current of a high
( 1Mhz) through the body to cause cutting and coagulation by local heating of the tissues
Degree of heating depends on the current density

Слайд 141

ELECTROCAUTERY

Two connections – neutral or patient plate and the active or cutting

ELECTROCAUTERY Two connections – neutral or patient plate and the active or
electrode
The same current flows through both plates
At the cutting electrode, heating or burning occurs because of the small area
No burning should occur at the neutral plate due to the large surface area

Слайд 142

ELECTROCAUTERY

If the neutral plate is not properly applied, the area of contact

ELECTROCAUTERY If the neutral plate is not properly applied, the area of
can be reduced so that burns can now result at points where the plate is in contact with skin.
If the neutral plate is completely detached, the current may return to the cautery unit via any point at which the patient is in contact with an earthed metal object

Слайд 143

ELECTROCAUTERY

Current density can reach a hazardous value when the electrosurgical current flows

ELECTROCAUTERY Current density can reach a hazardous value when the electrosurgical current
through parts of the body that have small cross sections
Current density can be increased by metallic prosthesis
Bipolar cautery

Слайд 144

ELECTROCAUTERY

Frequencies of 500 00- to 2000 000 Hz are used by electrocautery
Too

ELECTROCAUTERY Frequencies of 500 00- to 2000 000 Hz are used by
high to fibrillate the heart
Major concern is burn protection

Слайд 145

ELECTROCAUTERY

The grounding plate does not ground the patient to ground
It is the

ELECTROCAUTERY The grounding plate does not ground the patient to ground It
return electrode to the electrocautery unit
Ground plates should not be placed over metallic prosthesis

Слайд 146

CAPACITANCE

Is a measure of the ability of an object to hold electric

CAPACITANCE Is a measure of the ability of an object to hold
charge
Charge is the measure of the amount of electricity
Coulomb = amperes x seconds

Слайд 147

DEFIBRILLATOR

Is an example of an instrument in which electric charge is stored

DEFIBRILLATOR Is an example of an instrument in which electric charge is
and then released in a controlled fashion.

Слайд 148

BREATHING SYSTEMS

Open (non-rebreathing)
Simple face mask or nasal cannula (CO2 diffuses away

BREATHING SYSTEMS Open (non-rebreathing) Simple face mask or nasal cannula (CO2 diffuses
from the face)
Bag-Valve-Mask system (Ambu®): uses 3 valves to allow either spontaneous or controlled ventilation while preventing rebreathing

Слайд 149

BREATHING SYSTEMS

Semi-Open (Mapleson / Bain)
Most efficient removal of CO2 for a given

BREATHING SYSTEMS Semi-Open (Mapleson / Bain) Most efficient removal of CO2 for
gas flow when the "pop off" valve is nearest the source of the ventilatory power
Spontaneous ventilation: Mapleson A
Controlled ventilation: Mapleson D

Слайд 150

BREATHING SYSTEMS

However, the "A" system is very inefficient (requires high gas flows)

BREATHING SYSTEMS However, the "A" system is very inefficient (requires high gas
to prevent rebreathing during controlled ventilation, while the "D" system is reasonably efficient for both controlled and spontaneous ventilation, so the "D" is preferred for most applications.
Bain circuit is a coaxial Mapleson D

Слайд 151

BREATHING SYSTEMS

Semi Closed Circle System
Patient gas uptake < fresh gas flow <

BREATHING SYSTEMS Semi Closed Circle System Patient gas uptake Some rebreathing of
minute ventilation
Some rebreathing of exhaled gas (following removal of CO2 by absorber

Слайд 152

BREATHING SYSTEMS

Closed System
Gas inflow = Patient Uptake
If using sidestream agent

BREATHING SYSTEMS Closed System Gas inflow = Patient Uptake If using sidestream
/ CO2 analyzer, must route exhaust back into circuit
Starting values-O2: 3-4 ml/kg/min

Слайд 153

CO2 ABSORPTION

CO2 Absorption Granules
Small enough to have large surface area but

CO2 ABSORPTION CO2 Absorption Granules Small enough to have large surface area
large enough to avoid “channeling”
Typically 4-8 mesh

Слайд 154

CO2 ABSORPTION

Composition
Sodalime: NaOH, Ca(OH)2
Baralyme: KOH, Ca(OH)2, Ba(OH)2 -More likely to react

CO2 ABSORPTION Composition Sodalime: NaOH, Ca(OH)2 Baralyme: KOH, Ca(OH)2, Ba(OH)2 -More likely
with anesthetics to form CO (desflurane) or compound A (sevoflurane)
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