Содержание
- 2. Figure 2 Routes of Administration Intravenous Intranodal Subcutaneous Intradermal Tumor Lysate Whole tumor mRNA extracts Plasmacytoid
- 3. Priming modalities Personalized synthetic vaccine Boosting Synthetic vaccine Synthetic vaccine Synthetic vaccine Standard of care/ in
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Слайд 2Figure 2
Routes of Administration
Intravenous
Intranodal
Subcutaneous
Intradermal
Tumor Lysate
Whole tumor
mRNA extracts
Plasmacytoid DC
B cell
Immunogenic treatments
exosomes
Antigen types
HOCl oxidation
UV
Figure 2
Routes of Administration
Intravenous
Intranodal
Subcutaneous
Intradermal
Tumor Lysate
Whole tumor
mRNA extracts
Plasmacytoid DC
B cell
Immunogenic treatments
exosomes
Antigen types
HOCl oxidation
UV
Heat shock
hyperthermia
Principal APCs
Microneedle patches
3d synthetic scaffolds
Synthetic encapsulation
Routes of
administration
cDC1
cDC2
iDCs
macrophage
CD123+
CD11c-
CD303+
CD304+
CD123-
CD11c+
CD141+
Clec9A+
CD123-
CD11c+
CD1c+
Clec9A-
CD16-
CD11c+
CD19+
CD20+
liposome
Synthetic polymer
nsnoparticle
hydrogel
Слайд 3Priming modalities
Personalized synthetic vaccine
Boosting
Synthetic vaccine
Synthetic vaccine
Synthetic vaccine
Standard of care/ in situ approaches
Radiotherapy
Chemotherapy
Cryoablation
Immunomodulation
Whole
Priming modalities
Personalized synthetic vaccine
Boosting
Synthetic vaccine
Synthetic vaccine
Synthetic vaccine
Standard of care/ in situ approaches
Radiotherapy
Chemotherapy
Cryoablation
Immunomodulation
Whole
Patient interrogation
*
Blood collection and tumor biopsy
Слайд 4Info for the next slide:
Info for the next slide: