Toxicology 1 (4)
Text book Liptáková, D., Prachar, V., Valík Ľ.: Vybrané kapitoly zo všeobecnej, potravinárskej a nutričnej toxikológie. STU Bratislava, 2015.
The oldest records on poisons: methods of their synthesis – Eber´s papyrus (1,500 BC). Old Egyptians recognized: conium, digitalin, opioids, Pb and Cu compounds etc.
At the beginning of ancient Greek culture (400 BC), physician Hippokrates has broaden knowledge on poisons – dosages and usage of poisons and medicaménts.
The king Mithridates used sentenced to search for antidota against poisons – MITRIDATISM.
The source of toxicology → exploition of poisons in assassinations, suicides. Catherine di Medici tested poisons on powerty and sick people and observed clinical symptoms. Lucrezia Borgia (1480 – 1519, daughter of the pope Alexander VI) belonged to the famous poisoners – used poisons to eliminate political counterpartners.
TOXICOLOGY