Hemolytic anemia

Hemolytic Anemia
Hemolytic anemia is a disorder in which red blood cells are destroyed faster than they can be made. The destruction of red blood cells is called hemolysis.
Red blood cells carry oxygen to all parts of your body. If you have a lower than normal amount of red blood cells, you have anemia

Hemolytic anemia can be inherited or acquired
Inherited hemolytic anemia happens when parents pass the gene for the condition on to their children.
Acquired hemolytic anemia is not something you are born with. You develop the condition later.

What causes hemolytic anemia?
Inherited
With the inherited type, parents pass the genes for the condition on to their children. Two common causes of this type of anemia are sickle cell anemia and thalassemia. These conditions produce red blood cells that don’t live as long as normal red blood cells

What causes hemolytic anemia?
Acquired
Certain infections, which may be viral or bacterial Medicines, such as penicillin, antimalarial medicines,
Blood cancers
Autoimmune disorders, such as lupus, rheumatoid arthritis, or
ulcerative colitis
Certain tumors
An overactive spleen (hypersplenism)
Mechanical heart valves that may damage red blood cells as
they leave the heart

Symptoms
Abnormal paleness or lack of color of the skin
Yellowish skin, eyes, and mouth (jaundice)
Dark-colored urine
Fever
Weakness
Dizziness
Confusion
Can’t handle physical activity
Enlarged spleen and liver
Increased heart rate (tachycardia)
Heart murmur

Diagnosis
Complete blood count (CBC). This test measures many different parts of your blood.
Other blood tests. If the CBC test shows that you have anemia, you may have other blood tests. These can find out what type of anemia you have and how serious it is.
Urine test. This can check for hemoglobin (a protein in red blood cells) and iron.
Bone marrow aspiration or biopsy. This involves taking a small sample of bone marrow fluid (aspiration) or solid bone marrow tissue (called a core biopsy). The sample is usually taken from the hip bones. It is checked for the number, size, and maturity of blood cells or abnormal cells.